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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
17.88
Human Site:
S336
Identified Species:
30.26
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
S336
V
Q
K
S
S
H
R
S
G
F
I
R
L
G
S
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
S336
V
Q
K
S
S
H
R
S
G
F
I
R
L
G
S
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
R326
H
H
A
F
F
R
L
R
G
P
V
Q
K
S
S
Dog
Lupus familis
XP_532028
914
101864
S418
G
N
S
K
S
N
R
S
D
F
I
R
L
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
S336
V
Q
K
S
S
H
R
S
G
F
I
R
L
G
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
S336
V
Q
K
G
S
H
R
S
G
F
I
R
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
S336
V
P
T
Q
N
N
G
S
Q
A
W
G
L
R
P
Chicken
Gallus gallus
XP_422083
502
57358
I110
S
I
K
K
Q
V
K
I
G
P
P
Y
C
L
H
Frog
Xenopus laevis
NP_001080234
498
57093
K106
D
N
T
K
S
I
K
K
Q
V
K
I
G
P
P
Zebra Danio
Brachydanio rerio
O57457
619
70690
P227
E
Y
F
L
G
L
T
P
V
G
V
V
V
Y
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
Q351
V
K
G
P
S
A
R
Q
N
F
F
R
M
G
S
Honey Bee
Apis mellifera
XP_623974
809
90976
Q416
V
K
G
A
S
G
R
Q
N
F
F
R
M
G
S
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
V497
I
H
A
S
T
A
S
V
R
P
V
S
S
G
S
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
Q331
V
K
Q
Q
Q
G
R
Q
G
F
I
R
M
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
100
13.3
60
N.A.
100
93.3
N.A.
20
13.3
6.6
0
N.A.
46.6
46.6
20
53.3
P-Site Similarity:
100
100
26.6
66.6
N.A.
100
93.3
N.A.
33.3
20
13.3
13.3
N.A.
60
66.6
40
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
8
0
15
0
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
8
8
0
0
0
0
58
15
0
0
0
0
% F
% Gly:
8
0
15
8
8
15
8
0
50
8
0
8
8
65
0
% G
% His:
8
15
0
0
0
29
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
0
0
8
0
8
0
0
43
8
0
0
0
% I
% Lys:
0
22
36
22
0
0
15
8
0
0
8
0
8
0
8
% K
% Leu:
0
0
0
8
0
8
8
0
0
0
0
0
43
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
22
0
0
% M
% Asn:
0
15
0
0
8
15
0
0
15
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
0
8
0
22
8
0
0
8
15
% P
% Gln:
0
29
8
15
15
0
0
22
15
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
8
58
8
8
0
0
58
0
8
0
% R
% Ser:
8
0
8
29
58
0
8
43
0
0
0
8
8
8
72
% S
% Thr:
0
0
15
0
8
0
8
0
0
0
0
0
0
0
0
% T
% Val:
58
0
0
0
0
8
0
8
8
8
22
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _